News & Events

27 March 2024

Register now for exciting Masterclass on Reimbursement in Healthcare

Register here - free of charge! A-TANGO is opening its educational doors to anyone interested in extending their knowledge, specifically to the science and healthcare community: Louise Perrault, President and CEO of IMAC - International Market Access Consulting GmbH, gives a very relevant online Masterclass (via Zoom) about "Reimbursement in Healthcare - with relevance to new therapies in cirrhosis and acute-on-chronic liver failure (ACLF)" on Wednesday, 27 March 2024, 4-5 pm CET. Registration closes on 26 March 2024. Registrants will receive the Zoom link in due time via email.

9 January 2024

New podcast episode "The Patient-Doctor Relationship and Informed Consent" with Thomas Berg & Cornelius Engelmann

Explore the complexity of "The Patient-Doctor Relationship and Informed Consent" in the newest podcast episode of the “Interviews with Experts” series by Frances Hand. Join the conversation with Prof. Thomas Berg and Dr. Cornelius Engelmann as they dive into the significance of a robust doctor-patient relationship. Gain insights into the challenges surrounding informed consent amidst stressful decision-making.

Listen now on 🔗 Spotify!

27 November 2023

3-min survey about the effects of macroeconomic challenges on research in Europe

European researchers, especially project coordinators & supervisors of clinical trials, are asked to answer a few questions to help us understand how COVID-19, inflation, lack of qualified human resources, and other macro-economic factors and challenges have affected your research in the past 4 years: Click here to access the survey. It only takes 3 minutes to complete the survey and participation is entirely anonymous (unless an email address is entered at the end to receive the results of the survey once they are ready). We intend to collect more than 100 responses before closing the survey. - Thank you kindly for supporting our initiative!


More than 10 million people worldwide suffer from decompensated cirrhosis, often as a result of severe alcoholic hepatitis (sAH) or other chronic liver diseases. In its final stages, decompensated cirrhosis leads to acute-on-chronic liver failure (ACLF), a syndrome characterized by multi-organ failure. Effective treatment of ACLF is an urgent and unmet need. The A-TANGO consortium performs Phase 2 clinical studies of an innovative therapeutic strategy that targets inflammation and improves hepatocyte proliferation. We call this novel combinatorial therapy G-TAK. In addition, A-TANGO strives to identify reliable biomarkers for better patient stratification and an increased survival rate.

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  • Obtain ethical and regulatory approval of the planned clinical studies
  • Ensure safe and regulated supply of the required drugs and placebos
  • European multicenter clinical study to establish the safety, pharmacokinetics, and efficacy of our novel therapeutic strategy
  • Explore the pathophysiological mechanisms and evaluate biomarkers
  • Evaluate our results with respect to clinical outcome, treatment impact, and quality of life
  • Exploit our results by identifying economic benefits for the healthcare system, reimbursement strategies, and potential commercial interest
  • Disseminate the therapeutic potential of our novel treatment strategy to stakeholders and increase awareness of end-stage liver disease

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Prof. Dr. Rajiv Jalan (EF CLIF)
Travessera de Gràcia 11, 7th floor
08021 Barcelona


Dr. med. Cornelius Engelmann (Charité)
Augustenburger Platz 1
13353 Berlin


concentris research management gmbh
Ludwigstr. 4
82256 Fürstenfeldbruck